The minimum system requirements are meant for using SeqSphere+ with the tutorials or Sanger data only. SeqSphere+ server and client software can be installed on the same computer in such scenarios.
For startup and single user installations SeqSphere+ server and client software can be installed on the same computer (fulfilling the SeqSphere+ client RAM and server HD requirements). If more than one user is working with the same SeqSphere+ server separate computers for server and client(s) are recommended.
The SeqSphere+ server can easily be moved to another computer later.
Most computation is done on the client computer (e.g., assembling, etc.). Therefore, computational power and amount of RAM is more important on the client than on the server computer. Client and server communicate by default via port 8064 (configurable) over the Intra-/Internet. They should have a fastest possible network connection (e.g., 1 GB Ethernet).
If an increasing number of users are going to work with the same SeqSphere+ server simultaneously the simplest solution to accommodate for is to add additional client computers.
Assembling, importing, analyzing and typing of hundreds of your NGS sequence data can be done automatically without any user interaction by running SeqSphere+ clients in the pipeline mode. The workflow of a pipeline is defined by a pipeline script. Multiple clients can run the same pipeline script in parallel to speed-up or to scale-up for higher throughput.
To use the power of a probably available Linux high performance computer, the SeqSphere+ server and multiple instances of the SeqSphere+ client can be run on this computer. In pipeline mode the client can run without any graphical user interface. To visualize the analysis results of such pipelines the server can be accessed by additional clients installed on ordinary desktop computers with minimum requirements (e.g., 4-8 GB RAM).